Doyle suffered medial knee ligament damage during the Republic of Ireland's 2-1 European Championship win over Macedonia on Saturday night and was forced off after just 17 minutes.
Republic boss Giovanni Trapattoni claimed the 27-year-old would be out for between one and two months, which could see him miss Wolves' final eight games of the campaign.
Berra said: "It's a massive blow for us, he's a top player, he does a great job for us up front.
"But we've got good strikers on the bench in Sylvan Ebanks-Blake and Steven Fletcher, who have come in this season and done well and scored goals for us.
"So we won't be getting down about that, we'll move on."
Source: PA
Source: PA